• Western blot analysis of the lysates from HUVECcells using CHRM2 antibody.
  • Immunofluorescence analysis of LOVO cells, using CHRM2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HeLa and MCF-7 cells, using CHRM2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HeLa cells using mAChR M2 Polyclonal Antibody

Anti-CHRM2 antibody (185-234 aa) (STJ93977)

SKU:
STJ93977

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Muscarinic acetylcholine receptor M2 (185-234 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHRM2
Gene ID: 1129
Uniprot ID: ACM2_HUMAN
Immunogen Region: 185-234 aa
Specificity: mAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CHRM2 at the amino acid range 185-234
Function The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3).this then triggers calcium ion release into the cytosol.
Protein Name Muscarinic Acetylcholine Receptor M2
Database Links Reactome: R-HSA-390648
Reactome: R-HSA-418594
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Postsynaptic Cell Membrane
Phosphorylation In Response To Agonist Binding Promotes Receptor Internalization
Alternative Antibody Names Anti-Muscarinic Acetylcholine Receptor M2 antibody
Anti-CHRM2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance