Tissue Specificity | Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines. |
Function | Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and maintenance of vesicular membranes. |
Protein Name | Cholinephosphotransferase 1Hcpt1Aapt1-Like ProteinDiacylglycerol Cholinephosphotransferase 1 |
Database Links | Reactome: R-HSA-1483191 |
Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Cholinephosphotransferase 1 antibodyAnti-Hcpt1 antibodyAnti-Aapt1-Like Protein antibodyAnti-Diacylglycerol Cholinephosphotransferase 1 antibodyAnti-CHPT1 antibodyAnti-CPT1 antibodyAnti-MSTP022 antibody |
Information sourced from Uniprot.org