Anti-CHORDC1 antibody (STJA0008602)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CHORDC1
General Information
| Short Description | Rabbit polyclonal anti-Cysteine and histidine-rich domain-containing protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHORDC1 |
| Gene ID | 26973 |
| Uniprot ID | CHRD1_HUMAN |
| Immunogen | Synthesized peptide derived from human CHORDC1 |
| Specificity | This antibody detects endogenous levels of CHORDC1 at Human, Mouse, Rat |
Additional Info
| Function | Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis. |
| Protein Name | Cysteine And Histidine-Rich Domain-Containing Protein 1Chord Domain-Containing Protein 1Chord-Containing Protein 1Chp-1Protein Morgana |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Cysteine And Histidine-Rich Domain-Containing Protein 1 antibodyAnti-Chord Domain-Containing Protein 1 antibodyAnti-Chord-Containing Protein 1 antibodyAnti-Chp-1 antibodyAnti-Protein Morgana antibodyAnti-CHORDC1 antibodyAnti-CHP1 antibody |
Information sourced from Uniprot.org