| Host: | Goat |
| Applications: | WB |
| Reactivity: | Human/Rat/Mouse/Monkey/Canine |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Choroideremia (Rab escort protein 2) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: | 3 mg/mL |
| Dilution Range: | WB 1:500-1:5000 |
| Gene Symbol: | CHML |
| Gene ID: | 1122 |
| Uniprot ID: | RAE2_HUMAN |
| Accession Number: | ENSG00000203668 |
| Specificity: | Detects endogenous REP2 by Western blot. This Ab is specific for REP2, it does not cross-react with REP1. |
| Immunogen: | Purified recombinant human TNF alpha produced in E. coli. |
| Function | Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. |
| Protein Name | Rab Proteins Geranylgeranyltransferase Component A 2Choroideremia-Like ProteinRab Escort Protein 2Rep-2 |
| Database Links | Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Rab Proteins Geranylgeranyltransferase Component A 2 antibodyAnti-Choroideremia-Like Protein antibodyAnti-Rab Escort Protein 2 antibodyAnti-Rep-2 antibodyAnti-CHML antibodyAnti-REP2 antibody |
Information sourced from Uniprot.org
