• Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CHI3L1 antibody (STJ193191)

SKU:
STJ193191

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Chitinase-3-like protein 1 is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
WB 1:500-2000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CHI3L1
Gene ID: 1116
Uniprot ID: CH3L1_HUMAN
Specificity: This antibody detects endogenous levels of human GP-39
Immunogen: Synthesized peptide derived from the human GP-39
Post Translational Modifications Glycosylated.
Function Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
Protein Name Chitinase-3-Like Protein 1
39 Kda Synovial Protein
Cartilage Glycoprotein 39
Cgp-39
Gp-39
Hcgp-39
Ykl-40
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Extracellular Space
Cytoplasm
Perinuclear Region
Endoplasmic Reticulum
Alternative Antibody Names Anti-Chitinase-3-Like Protein 1 antibody
Anti-39 Kda Synovial Protein antibody
Anti-Cartilage Glycoprotein 39 antibody
Anti-Cgp-39 antibody
Anti-Gp-39 antibody
Anti-Hcgp-39 antibody
Anti-Ykl-40 antibody
Anti-CHI3L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance