| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHD2 (242-501) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHD2 |
| Gene ID: |
1106 |
| Uniprot ID: |
CHD2_HUMAN |
| Immunogen Region: |
242-501 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 242-501 of human CHD2 (NP_001036037.1). |
| Immunogen Sequence: |
SDDLIEMTGEGVDEQQDNSE TIEKVLDSRLGKKGATGAST TVYAIEANGDPSGDFDTEKD EGEIQYLIKWKGWSYIHSTW ESEESLQQQKVKGLKKLENF KKKEDEIKQWLGKVSPEDVE YFNCQQELASELNKQYQIVE RVIAVKTSKSTLGQTDFPAH SRKPAPSNEPEYLCKWMGLP YSECSWEDEALIGKKFQNCI DSFHSRNNSKTIPTRECKAL KQRPRFVALKKQPAYLGGE |
| Function | DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 2Chd-2Atp-Dependent Helicase Chd2 |
| Cellular Localisation | NucleusBinds To Myogenic Gene Promoters |
| Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 2 antibodyAnti-Chd-2 antibodyAnti-Atp-Dependent Helicase Chd2 antibodyAnti-CHD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
