| Short Description : | Goat polyclonal antibody anti-CFC1/Cripto-1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave an approx 55kDa band in Human Breast, Placenta and Testis lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanatio |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CFC1 |
| Gene ID: | 55997 |
| Uniprot ID: | CFC1_HUMAN |
| Accession Number: | NP_115934.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | HFTGRYCEHDQRRSEC |
| Function | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. |
| Protein Name | Cryptic ProteinCryptic Family Protein 1 |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecretedDoes Not Exhibit A Typical Gpi-Signal SequenceThe C-Ter Hydrophilic Extension Of The Gpi-Signal Sequence Reduces The Efficiency Of Processing And Could Lead To The Production Of An Secreted Unprocessed FormThis Extension Is Found Only In Primates |
| Alternative Antibody Names | Anti-Cryptic Protein antibodyAnti-Cryptic Family Protein 1 antibodyAnti-CFC1 antibody |
Information sourced from Uniprot.org
