Host: | Goat |
Applications: | Pep-ELISA/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-CFC1/Cripto-1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave an approx 55kDa band in Human Breast, Placenta and Testis lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanatio |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | CFC1 |
Gene ID: | 55997 |
Uniprot ID: | CFC1_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_115934.1 |
Immunogen Sequence: | HFTGRYCEHDQRRSEC |
Function | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. |
Protein Name | Cryptic ProteinCryptic Family Protein 1 |
Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecretedDoes Not Exhibit A Typical Gpi-Signal SequenceThe C-Ter Hydrophilic Extension Of The Gpi-Signal Sequence Reduces The Efficiency Of Processing And Could Lead To The Production Of An Secreted Unprocessed FormThis Extension Is Found Only In Primates |
Alternative Antibody Names | Anti-Cryptic Protein antibodyAnti-Cryptic Family Protein 1 antibodyAnti-CFC1 antibody |
Information sourced from Uniprot.org