Anti-CFC1/Cripto-1 antibody (Internal) (STJ70759)

SKU:
STJ70759-100
£312.50
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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-CFC1/Cripto-1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Preliminary experiments gave an approx 55kDa band in Human Breast, Placenta and Testis lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanatio
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CFC1
Gene ID: 55997
Uniprot ID: CFC1_HUMAN
Immunogen Region: Internal
Accession Number: NP_115934.1
Immunogen Sequence: HFTGRYCEHDQRRSEC
Function NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.
Protein Name Cryptic Protein
Cryptic Family Protein 1
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Does Not Exhibit A Typical Gpi-Signal Sequence
The C-Ter Hydrophilic Extension Of The Gpi-Signal Sequence Reduces The Efficiency Of Processing And Could Lead To The Production Of An Secreted Unprocessed Form
This Extension Is Found Only In Primates
Alternative Antibody Names Anti-Cryptic Protein antibody
Anti-Cryptic Family Protein 1 antibody
Anti-CFC1 antibody

Information sourced from Uniprot.org