• Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-CES2 antibody (Internal) (STJ92239)

SKU:
STJ92239

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cocaine esterase (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CES2
Gene ID: 8824
Uniprot ID: EST2_HUMAN
Immunogen Region: Internal
Specificity: CES2 Polyclonal Antibody detects endogenous levels of CES2 protein.
Immunogen: Synthesized peptide derived from the Internal region of human CES2.
Post Translational Modifications Glycosylated.
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins.
Protein Name Cocaine Esterase
Carboxylesterase 2
Ce-2
Hce-2
Methylumbelliferyl-Acetate Deacetylase 2
Database Links Reactome: R-HSA-211945
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Antibody Names Anti-Cocaine Esterase antibody
Anti-Carboxylesterase 2 antibody
Anti-Ce-2 antibody
Anti-Hce-2 antibody
Anti-Methylumbelliferyl-Acetate Deacetylase 2 antibody
Anti-CES2 antibody
Anti-ICE antibody

Information sourced from Uniprot.org

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