| Post Translational Modifications | Phosphorylated at the C-terminus by CK2. |
| Function | Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA.C16:0-CoA). Can use other acyl donors, but with less efficiency. N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a role in de novo ceramide synthesis and surfactant homeostasis in pulmonary epithelia. |
| Protein Name | Ceramide Synthase 5Cers5Lag1 Longevity Assurance Homolog 5Sphingoid Base N-Palmitoyltransferase Cers5Sphingosine N-Acyltransferase Cers5 |
| Database Links | Reactome: R-HSA-1660661 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ceramide Synthase 5 antibodyAnti-Cers5 antibodyAnti-Lag1 Longevity Assurance Homolog 5 antibodyAnti-Sphingoid Base N-Palmitoyltransferase Cers5 antibodyAnti-Sphingosine N-Acyltransferase Cers5 antibodyAnti-CERS5 antibodyAnti-LASS5 antibody |
Information sourced from Uniprot.org
