| Short Description : | Mouse monoclonal anti-Cerebral dopamine neurotrophic factor for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | IgG |
| Dilution Range: | WB 1:2000-1:4000 |
| Formulation: | PBS pH 7.4, with 0.1% sodium azide |
| Storage Instruction: | Store at-20°C or-70°C upon receipt. After opening maintain undiluted in smaller aliquots at-20°C or-70°C for up to 6 months. Avoid multiple freeze-thaw cycles. |
| Gene Symbol: | CDNF |
| Gene ID: | 441549 |
| Uniprot ID: | CDNF_HUMAN |
| Immunogen: | Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant. |
| Immunogen Sequence: | Human |
| Specificity: | CDNF (conserved dopamine neurotrophic factor). |
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org
