Anti-Cerebral dopamine neurotrophic factor antibody (STJA0040776)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenRecombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
General Information
| Short Description | Mouse monoclonal anti-Cerebral dopamine neurotrophic factor for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | IgG |
| Dilution Range | WB 1:2000-1:4000 |
| Formulation | PBS pH 7.4, with 0.1% sodium azide |
| Storage Instruction | Store at-20ยฐC or-70ยฐC upon receipt. After opening maintain undiluted in smaller aliquots at-20ยฐC or-70ยฐC for up to 6 months. Avoid multiple freeze-thaw cycles. |
Target Information
| Gene Symbol | CDNF |
| Gene ID | 441549 |
| Uniprot ID | CDNF_HUMAN |
| Immunogen | Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant. |
| Immunogen Sequence | Human |
| Specificity | CDNF (conserved dopamine neurotrophic factor). |
Additional Info
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org