| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CER1 |
| Gene ID: | 9350 |
| Uniprot ID: | CER1_HUMAN |
| Immunogen Region: | 18-267 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human CER1 (NP_005445.1). |
| Immunogen Sequence: | TRHQDGRQNQSSLSPVLLPR NQRELPTGNHEEAEEKPDLF VAVPHLVATSPAGEGQRQRE KMLSRFGRFWKKPEREMHPS RDSDSEPFPPGTQSLIQPID GMKMEKSPLREEAKKFWHHF MFRKTPASQGVILPIKSHEV HWETCRTVPFSQTITHEGCE KVVVQNNLCFGKCGSVHFPG AAQHSHTSCSHCLPAKFTTM HLPLNCTELSSVIKVVMLVE ECQCKVKTEHEDGHILHAG |
| Post Translational Modifications | N-glycosylated. |
| Function | Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. |
| Protein Name | CerberusCerberus-Related ProteinDan Domain Family Member 4 |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerberus antibodyAnti-Cerberus-Related Protein antibodyAnti-Dan Domain Family Member 4 antibodyAnti-CER1 antibodyAnti-DAND4 antibody |
Information sourced from Uniprot.org