• Hela whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-CEA (ABT-CEA) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: HelaPredicted band size: 76kDaObserved band size: 200kDa
  • Human colon carcinoma tissue was stained with anti-CEA (ABT-CEA) antibody.
  • Human colon carcinoma tissue was stained with anti-CEA (ABT-CEA) antibody.
  • Human lung adenocarcinoma tissue was stained with anti-CEA (ABT-CEA) antibody.
  • Human pancreatic adenocarcinoma tissue was stained with anti-CEA (ABT-CEA) antibody.

Anti-CEACAM5 antibody (600-702 aa) [ABT-CEA] (STJ196753)

SKU:
STJ196753

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/WB/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Carcinoembryonic antigen-related cell adhesion molecule 5 (600-702 aa) is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT-CEA
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
WB 1:200-1000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CEACAM5
Gene ID: 1048
Uniprot ID: CEAM5_HUMAN
Immunogen Region: 600-702 aa
Specificity: This antibody detects endogenous levels of human carcinoembryonic antigen (CEA). Antibody is negative with no cross reaction to BGP or NCA. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was
Immunogen: Synthesized peptide derived from the human carcinoembryonic antigen (CEA) at the amino acid range 600-702
Post Translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Protein Name Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
Carcinoembryonic Antigen
Cea
Meconium Antigen 100
Cd Antigen Cd66e
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Antibody Names Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 antibody
Anti-Carcinoembryonic Antigen antibody
Anti-Cea antibody
Anti-Meconium Antigen 100 antibody
Anti-Cd Antigen Cd66e antibody
Anti-CEACAM5 antibody
Anti-CEA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance