Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDKA2 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-CDK2AP2 antibody (51-100 aa) (STJ92755)

SKU:
STJ92755
£48.00 - £252.00
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Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Cyclin-dependent kinase 2-associated protein 2 (51-100 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDK2AP2
Gene ID: 10263
Uniprot ID: CDKA2_HUMAN
Immunogen Region: 51-100 aa
Specificity: DOC-1R Polyclonal Antibody detects endogenous levels of DOC-1R protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CDKA2 at the amino acid range 51-100
Post Translational Modifications Phosphorylated by MAPK1 and CDK2.
Function Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation.represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes.
Protein Name Cyclin-Dependent Kinase 2-Associated Protein 2
Cdk2-Associated Protein 2
Doc-1-Related Protein
Doc-1r
Cellular Localisation Cytoplasm
Nucleus
Accumulates In Immature Oocytes In The Nucleus
During The First Meiotic Division
Accumulates In The Cytoplasm And Localizes In Dots In The Vicinity Of The Chromosomes In A Region Enriched In Microtubules
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 2-Associated Protein 2 antibody
Anti-Cdk2-Associated Protein 2 antibody
Anti-Doc-1-Related Protein antibody
Anti-Doc-1r antibody
Anti-CDK2AP2 antibody
Anti-DOC1R antibody

Information sourced from Uniprot.org

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