| Function | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. |
| Protein Name | BorealinCell Division Cycle-Associated Protein 8Dasra-BHdasra-BPluripotent Embryonic Stem Cell-Related Gene 3 Protein |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-4615885Reactome: R-HSA-5663220Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusNucleolusCytoplasmCytoskeletonSpindleChromosomeCentromereLocalizes On Chromosome Arms And Inner Centromeres From Prophase Through Metaphase And Then Transferring To The Spindle Midzone And Midbody From Anaphase Through CytokinesisColocalizes With Senp3 In The Nucleolus In Interphase Cells |
| Alternative Antibody Names | Anti-Borealin antibodyAnti-Cell Division Cycle-Associated Protein 8 antibodyAnti-Dasra-B antibodyAnti-Hdasra-B antibodyAnti-Pluripotent Embryonic Stem Cell-Related Gene 3 Protein antibodyAnti-CDCA8 antibodyAnti-PESCRG3 antibody |
Information sourced from Uniprot.org
