| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDC6 (1-560) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDC6 |
| Gene ID: |
990 |
| Uniprot ID: |
CDC6_HUMAN |
| Immunogen Region: |
1-560 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-560 of human Cdc6 (Q99741). |
| Immunogen Sequence: |
MPQTRSQAQATISFPKRKLS RALNKAKNSSDAKLEPTNVQ TVTCSPRVKALPLSPRKRLG DDNLCNTPHLPPCSPPKQGK KENGPPHSHTLKGRRLVFDN QLTIKSPSKRELAKVHQNKI LSSVRKSQEITTNSEQRCPL KKESACVRLFKQEGTCYQQA KLVLNTAVPDRLPAREREMD VIRNFLREHICGKKAGSLYL SGAPGTGKTACLSRILQDLK KELKGFKTIMLNCMSLRTA |
| Post Translational Modifications | Ubiquitinated by the SCF(CCNF) E3 ubiquitin-protein ligase complex. |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
| Protein Name | Cell Division Control Protein 6 HomologCdc6-Related ProteinCdc18-Related ProteinHscdc18P62(Cdc6Hscdc6 |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-176187Reactome: R-HSA-68689Reactome: R-HSA-68867Reactome: R-HSA-68949Reactome: R-HSA-68962Reactome: R-HSA-69017Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusCytoplasmThe Protein Is Nuclear In G1 And Cytoplasmic In S-Phase Cells |
| Alternative Antibody Names | Anti-Cell Division Control Protein 6 Homolog antibodyAnti-Cdc6-Related Protein antibodyAnti-Cdc18-Related Protein antibodyAnti-Hscdc18 antibodyAnti-P62(Cdc6 antibodyAnti-Hscdc6 antibodyAnti-CDC6 antibodyAnti-CDC18L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
