| Short Description : | Rabbit monoclonal anti-CDC45 for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ICC/IF/FC |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R05-9F6 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CDC45 |
| Gene ID: | 8318 |
| Uniprot ID: | CDC45_HUMAN |
| Immunogen: | A synthesized peptide derived from human CDC45 |
| Tissue Specificity | Widely expressed, highest levels are found in adult testis and thymus and in fetal liver. |
| Function | Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. |
| Protein Name | Cell Division Control Protein 45 HomologPorc-Pi-1 |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-176974Reactome: R-HSA-68962Reactome: R-HSA-69205 |
| Cellular Localisation | NucleusChromosomeAssociates With Chromatin |
| Alternative Antibody Names | Anti-Cell Division Control Protein 45 Homolog antibodyAnti-Porc-Pi-1 antibodyAnti-CDC45 antibodyAnti-CDC45L antibodyAnti-CDC45L2 antibodyAnti-UNQ374 antibodyAnti-PRO710 antibody |
Information sourced from Uniprot.org
