Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-T-Cell Surface Protein Tactile antibodyAnti-Cell Surface Antigen Cd96 antibodyAnti-T Cell-Activated Increased Late Expression Protein antibodyAnti-Cd Antigen Cd96 antibodyAnti-CD96 antibody |
Information sourced from Uniprot.org