Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-T-Cell Surface Protein Tactile (270-370) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CD96 |
Gene ID: |
10225 |
Uniprot ID: |
TACT_HUMAN |
Immunogen Region: |
270-370 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human CD96 (NP_937839.1). |
Immunogen Sequence: |
EIPVIVENNSTDVLVERRFT CLLKNVFPKANITWFIDGSF LHDEKEGIYITNEERKGKDG FLELKSVLTRVHSNKPAQSD NLTIWCMALSPVPGNKVWNI S |
Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
Function | May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. |
Protein Name | T-Cell Surface Protein TactileCell Surface Antigen Cd96T Cell-Activated Increased Late Expression ProteinCd Antigen Cd96 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-T-Cell Surface Protein Tactile antibodyAnti-Cell Surface Antigen Cd96 antibodyAnti-T Cell-Activated Increased Late Expression Protein antibodyAnti-Cd Antigen Cd96 antibodyAnti-CD96 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance