| Host: |
Mouse |
| Applications: |
FC/IP |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD80 is suitable for use in Flow Cytometry and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
MEM-233 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Gene Symbol: |
CD80 |
| Gene ID: |
941 |
| Uniprot ID: |
CD80_HUMAN |
| Immunogen: |
Extracellular domain of human CD80 fused to human IgG1 (Fc) |
| Tissue Specificity | Expressed on activated B-cells, macrophages and dendritic cells. |
| Function | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B. |
| Protein Name | T-Lymphocyte Activation Antigen Cd80Activation B7-1 AntigenBb1Ctla-4 Counter-Receptor B7.1B7Cd Antigen Cd80 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-2219530Reactome: R-HSA-389356Reactome: R-HSA-389357Reactome: R-HSA-389359Reactome: R-HSA-389513Reactome: R-HSA-6783783Reactome: R-HSA-6811558 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-T-Lymphocyte Activation Antigen Cd80 antibodyAnti-Activation B7-1 Antigen antibodyAnti-Bb1 antibodyAnti-Ctla-4 Counter-Receptor B7.1 antibodyAnti-B7 antibodyAnti-Cd Antigen Cd80 antibodyAnti-CD80 antibodyAnti-CD28LG antibodyAnti-CD28LG1 antibodyAnti-LAB7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
