Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CD72 (120-359) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CD72 |
Gene ID: |
971 |
Uniprot ID: |
CD72_HUMAN |
Immunogen Region: |
120-359 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 120-359 of human CD72 (NP_001773.1). |
Immunogen Sequence: |
QVSQQLQQTNRVLEVTNSSL RQQLRLKITQLGQSAEDLQG SRRELAQSQEALQVEQRAHQ AAEGQLQACQADRQKTKETL QSEEQQRRALEQKLSNMENR LKPFFTCGSADTCCPSGWIM HQKSCFYISLTSKNWQESQK QCETLSSKLATFSEIYPQSH SYYFLNSLLPNGGSGNSYWT GLSSNKDWKLTDDTQRTRTY AQSSKCNKVHKTWSWWTLES ESCRSSLPYICEMTAFRFP |
Tissue Specificity | Pre-B-cells and B-cells but not terminally differentiated plasma cells. |
Post Translational Modifications | Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1. |
Function | Plays a role in B-cell proliferation and differentiation. |
Protein Name | B-Cell Differentiation Antigen Cd72Lyb-2Cd Antigen Cd72 |
Database Links | Reactome: R-HSA-416700 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-B-Cell Differentiation Antigen Cd72 antibodyAnti-Lyb-2 antibodyAnti-Cd Antigen Cd72 antibodyAnti-CD72 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance