Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)

Anti-CD66e/CEA/CEACAM5 nanobody [SAA1298] (STJN000113)

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STJN000113
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA/FC/SPR
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Cell Adhesion Molecule Ceacam5 is suitable for use in ELISA, Flow Cytometry and SPR research applications.
Clonality : Monoclonal
Clone ID : SAA1298
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: CEACAM5
Gene ID: 1048
Uniprot ID: CEAM5_HUMAN
Post Translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Protein Name Cell Adhesion Molecule Ceacam5
Carcinoembryonic Antigen
Cea
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
Cea Cell Adhesion Molecule 5
Meconium Antigen 100
Cd Antigen Cd66e
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Nanobody Names Anti-Cell Adhesion Molecule Ceacam5 nanobody
Anti-Carcinoembryonic Antigen nanobody
Anti-Cea nanobody
Anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 nanobody
Anti-Cea Cell Adhesion Molecule 5 nanobody
Anti-Meconium Antigen 100 nanobody
Anti-Cd Antigen Cd66e nanobody
Anti-CEACAM5 nanobody
Anti-CEA nanobody

Information sourced from Uniprot.org

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