Anti-CD40 antibody [LOB7/6] (STJ16100844)

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STJ16100844-02
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Short Description :Mouse monoclonal anti-CD40 for use in IHC-P, FC, IHC-F and IP in Human and Dog samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P/FC/IHC-F/IP
Host:Mouse
Reactivity:Human/Dog
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :LOB7/6
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1.0 mg/mL
Formulation:TBS
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:CD40
Gene ID:958
Uniprot ID:TNR5_HUMAN
Immunogen:CD40 Ig (Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG.
Tissue Specificity B-cells and in primary carcinomas.
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 antibody
Anti-B-Cell Surface Antigen Cd40 antibody
Anti-Bp50 antibody
Anti-Cd40l Receptor antibody
Anti-Cdw40 antibody
Anti-Cd Antigen Cd40 antibody
Anti-CD40 antibody
Anti-TNFRSF5 antibody

Information sourced from Uniprot.org