Host: |
Mouse |
Applications: |
IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD34 is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
QBEnd‐10 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1/Kappa |
Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
Purification: |
Affinity purified |
Dilution Range: |
1:100‐200 |
Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: |
CD34 |
Gene ID: |
947 |
Uniprot ID: |
CD34_HUMAN |
Specificity: |
Positive control: Hemangioma |
Immunogen: |
Detergent solubilized vesicular suspension prepared from a perfusate of human term placenta |
Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
Post Translational Modifications | Highly glycosylated. Phosphorylated on serine residues by PKC. |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Protein Name | Hematopoietic Progenitor Cell Antigen Cd34Cd Antigen Cd34 |
Database Links | Reactome: R-HSA-198933 P28906-1 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Hematopoietic Progenitor Cell Antigen Cd34 antibodyAnti-Cd Antigen Cd34 antibodyAnti-CD34 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance