| Host: |
Alpaca |
| Applications: |
Blocking/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Alpaca monoclonal nanobody anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A is suitable for use in Universaling and ELISA research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA2150 |
| Conjugation: |
Unconjugated |
| Isotype: |
VHH-8His-Cys-tag |
| Formulation: |
0.01M PBS, pH 7.4. |
| Purification: |
Purified by Nickel column. |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A nanobodyAnti-Igg Fc Receptor Ii-A nanobodyAnti-Cdw32 nanobodyAnti-Fc-Gamma Rii-A nanobodyAnti-Fc-Gamma-Riia nanobodyAnti-Fcrii-A nanobodyAnti-Cd Antigen Cd32 nanobodyAnti-FCGR2A nanobodyAnti-CD32 nanobodyAnti-FCG2 nanobodyAnti-FCGR2A1 nanobodyAnti-IGFR2 nanobody |
Information sourced from Uniprot.org
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