Anti-CD312/ADGRE2/EMR2 antibody [SAA1811] (STJA0020239)

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STJA0020239
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Adhesion G Protein-Coupled Receptor E2 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1811
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: ADGRE2
Gene ID: 30817
Uniprot ID: AGRE2_HUMAN
Post Translational Modifications Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation.
Protein Name Adhesion G Protein-Coupled Receptor E2
Egf-Like Module Receptor 2
Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2
Cd Antigen Cd312
Database Links Reactome: R-HSA-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Ruffle Membrane
Localized At The Leading Edge Of Migrating Cells
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor E2 antibody
Anti-Egf-Like Module Receptor 2 antibody
Anti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2 antibody
Anti-Cd Antigen Cd312 antibody
Anti-ADGRE2 antibody
Anti-EMR2 antibody

Information sourced from Uniprot.org