Anti-CD303/CLEC4C antibody [201A] {APC} (STJA0001926)

SKU:
STJA0001926

Current Stock:
Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-C-type lectin domain family 4 member C is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 201A
Conjugation: APC
Isotype: IgG2ak
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: CLEC4C
Gene ID: 170482
Uniprot ID: CLC4C_HUMAN
Tissue Specificity Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
Function Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Protein Name C-Type Lectin Domain Family 4 Member C
Blood Dendritic Cell Antigen 2
Bdca-2
C-Type Lectin Superfamily Member 7
Dendritic Lectin
Cd Antigen Cd303
Database Links Reactome: R-HSA-5621480
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-C-Type Lectin Domain Family 4 Member C antibody
Anti-Blood Dendritic Cell Antigen 2 antibody
Anti-Bdca-2 antibody
Anti-C-Type Lectin Superfamily Member 7 antibody
Anti-Dendritic Lectin antibody
Anti-Cd Antigen Cd303 antibody
Anti-CLEC4C antibody
Anti-BDCA2 antibody
Anti-CLECSF11 antibody
Anti-CLECSF7 antibody
Anti-DLEC antibody
Anti-HECL antibody
Anti-UNQ9361 antibody
Anti-PRO34150 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance