| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CD300LB (1-201) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CD300LB |
| Gene ID: |
124599 |
| Uniprot ID: |
CLM7_HUMAN |
| Immunogen Region: |
1-201 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human CD300LB (NP_777552.3). |
| Immunogen Sequence: |
MWLPPALLLLSLSGCFSIQG PESVRAPEQGSLTVQCHYKQ GWETYIKWWCRGVRWDTCKI LIETRGSEQGEKSDRVSIKD NQKDRTFTVTMEGLRRDDAD VYWCGIERRGPDLGTQVKVI VDPEGAASTTASSPTNSNMA VFIGSHKRNHYMLLVFVKVP ILLILVTAILWLKGSQRVPE EPGEQPIYMNFSEPLTKDMA T |
| Tissue Specificity | Expressed exclusively in myeloid lineages. |
| Post Translational Modifications | Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2. |
| Function | Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. |
| Protein Name | Cmrf35-Like Molecule 7Clm-7Cd300 Antigen-Like Family Member BCmrf35-A2Immune Receptor Expressed On Myeloid Cells 3Irem-3Leukocyte Mono-Ig-Like Receptor 5Triggering Receptor Expressed On Myeloid Cells 5Trem-5Cd Antigen Cd300b |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cmrf35-Like Molecule 7 antibodyAnti-Clm-7 antibodyAnti-Cd300 Antigen-Like Family Member B antibodyAnti-Cmrf35-A2 antibodyAnti-Immune Receptor Expressed On Myeloid Cells 3 antibodyAnti-Irem-3 antibodyAnti-Leukocyte Mono-Ig-Like Receptor 5 antibodyAnti-Triggering Receptor Expressed On Myeloid Cells 5 antibodyAnti-Trem-5 antibodyAnti-Cd Antigen Cd300b antibodyAnti-CD300LB antibodyAnti-CD300B antibodyAnti-CLM7 antibodyAnti-CMRF35A2 antibodyAnti-IREM3 antibodyAnti-LMIR5 antibodyAnti-TREM5 antibodyAnti-UNQ2530 antibodyAnti-PRO6029 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
