Anti-CD300LB antibody (1-201) (STJ11103366)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD300LB (1-201) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CD300LB |
| Gene ID | 124599 |
| Uniprot ID | CLM7_HUMAN |
| Immunogen Region | 1-201 |
| Immunogen Sequence | MWLPPALLLLSLSGCFSIQG PESVRAPEQGSLTVQCHYKQ GWETYIKWWCRGVRWDTCKI LIETRGSEQGEKSDRVSIKD NQKDRTFTVTMEGLRRDDAD VYWCGIERRGPDLGTQVKVI VDPEGAASTTASSPTNSNMA VFIGSHKRNHYMLLVFVKVP ILLILVTAILWLKGSQRVPE EPGEQPIYMNFSEPLTKDMA T |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human CD300LB (NP_777552.3). |
Additional Info
| Tissue Specificity | Expressed exclusively in myeloid lineages. |
| Post Translational Modifications | Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2. |
| Function | Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. |
| Protein Name | Cmrf35-Like Molecule 7Clm-7Cd300 Antigen-Like Family Member BCmrf35-A2Immune Receptor Expressed On Myeloid Cells 3Irem-3Leukocyte Mono-Ig-Like Receptor 5Triggering Receptor Expressed On Myeloid Cells 5Trem-5Cd Antigen Cd300b |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-2172127 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cmrf35-Like Molecule 7 antibodyAnti-Clm-7 antibodyAnti-Cd300 Antigen-Like Family Member B antibodyAnti-Cmrf35-A2 antibodyAnti-Immune Receptor Expressed On Myeloid Cells 3 antibodyAnti-Irem-3 antibodyAnti-Leukocyte Mono-Ig-Like Receptor 5 antibodyAnti-Triggering Receptor Expressed On Myeloid Cells 5 antibodyAnti-Trem-5 antibodyAnti-Cd Antigen Cd300b antibodyAnti-CD300LB antibodyAnti-CD300B antibodyAnti-CLM7 antibodyAnti-CMRF35A2 antibodyAnti-IREM3 antibodyAnti-LMIR5 antibodyAnti-TREM5 antibodyAnti-UNQ2530 antibodyAnti-PRO6029 antibody |
Information sourced from Uniprot.org