Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CD2 (235-351) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CD2 |
Gene ID: |
914 |
Uniprot ID: |
CD2_HUMAN |
Immunogen Region: |
235-351 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 235-351 of human CD2 (NP_001758.2). |
Immunogen Sequence: |
TKRKKQRSRRNDEELETRAH RVATEERGRKPHQIPASTPQ NPATSQHPPPPPGHRSQAPS HRPPPPGHRVQHQPQKRPPA PSGTQVHQQKGPPLPRPRVQ PKPPHGAAENSLSPSSN |
Tissue Specificity | Expressed in natural killer cells (at protein level). |
Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
Protein Name | T-Cell Surface Antigen Cd2Erythrocyte ReceptorLfa-2Lfa-3 ReceptorRosette ReceptorT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
Database Links | Reactome: R-HSA-202733 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-T-Cell Surface Antigen Cd2 antibodyAnti-Erythrocyte Receptor antibodyAnti-Lfa-2 antibodyAnti-Lfa-3 Receptor antibodyAnti-Rosette Receptor antibodyAnti-T-Cell Surface Antigen T11/Leu-5 antibodyAnti-Cd Antigen Cd2 antibodyAnti-CD2 antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance