Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CD151 (113-253) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CD151 |
Gene ID: |
977 |
Uniprot ID: |
CD151_HUMAN |
Immunogen Region: |
113-253 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 113-253 of human CD151 (NP_004348.2). |
Immunogen Sequence: |
AYYQQLNTELKENLKDTMTK RYHQPGHEAVTSAVDQLQQE FHCCGSNNSQDWRDSEWIRS QEAGGRVVPDSCCKTVVALC GQRDHASNIYKVEGGCITKL ETFIQEHLR |
Tissue Specificity | Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes. |
Post Translational Modifications | Palmitoylated. Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion. |
Function | Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. (Microbial infection) Plays a role in human papillomavirus 16/HPV-16 endocytosis upon binding to cell surface receptor. |
Protein Name | Cd151 AntigenGp27Membrane Glycoprotein Sfa-1Platelet-Endothelial Tetraspan Antigen 3Peta-3Tetraspanin-24Tspan-24Cd Antigen Cd151 |
Database Links | Reactome: R-HSA-2022090Reactome: R-HSA-446107 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Cd151 Antigen antibodyAnti-Gp27 antibodyAnti-Membrane Glycoprotein Sfa-1 antibodyAnti-Platelet-Endothelial Tetraspan Antigen 3 antibodyAnti-Peta-3 antibodyAnti-Tetraspanin-24 antibodyAnti-Tspan-24 antibodyAnti-Cd Antigen Cd151 antibodyAnti-CD151 antibodyAnti-TSPAN24 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance