| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Transmembrane Protein Pvrig for use in FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | CPA.7.021 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | PVRIG |
| Gene ID: | 79037 |
| Uniprot ID: | PVRIG_HUMAN |
| Function | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. |
| Protein Name | Transmembrane Protein PvrigCd112 ReceptorCd112rPoliovirus Receptor-Related Immunoglobulin Domain-Containing Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protein Pvrig antibodyAnti-Cd112 Receptor antibodyAnti-Cd112r antibodyAnti-Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein antibodyAnti-PVRIG antibodyAnti-C7orf15 antibody |
Information sourced from Uniprot.org