Anti-CD112R/PVRIG antibody [CPA.7.021] (STJA0026938)

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STJA0026938
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Transmembrane Protein Pvrig is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : CPA.7.021
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: PVRIG
Gene ID: 79037
Uniprot ID: PVRIG_HUMAN
Function Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Protein Name Transmembrane Protein Pvrig
Cd112 Receptor
Cd112r
Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Transmembrane Protein Pvrig antibody
Anti-Cd112 Receptor antibody
Anti-Cd112r antibody
Anti-Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein antibody
Anti-PVRIG antibody
Anti-C7orf15 antibody

Information sourced from Uniprot.org

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