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Anti-MME antibody (491-540 aa) (STJ96715)

Western blot analysis of lysate from A549 cells, using MME Antibody.
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
Western blot analysis of A549 cells using CD10 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-MME antibody (491-540 aa) (STJ96715)

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STJ96715

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Neprilysin (491-540 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MME
Gene ID:	4311
Uniprot ID:	NEP_HUMAN
Immunogen Region:	491-540 aa
Specificity:	CD10 Polyclonal Antibody detects endogenous levels of CD10 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the Internal region of human MME at the amino acid range 491-540

Function	Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Protein Name	Neprilysin Atriopeptidase Common Acute Lymphocytic Leukemia Antigen Calla Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10
Database Links	Reactome: R-HSA-2022377 Reactome: R-HSA-5578768 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-Neprilysin antibody Anti-Atriopeptidase antibody Anti-Common Acute Lymphocytic Leukemia Antigen antibody Anti-Calla antibody Anti-Enkephalinase antibody Anti-Neutral Endopeptidase 24.11 antibody Anti-Nep antibody Anti-Neutral Endopeptidase antibody Anti-Skin Fibroblast Elastase antibody Anti-Sfe antibody Anti-Cd Antigen Cd10 antibody Anti-MME antibody Anti-EPN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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