| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCR8 |
| Gene ID: | 1237 |
| Uniprot ID: | CCR8_HUMAN |
| Immunogen Region: | 250-355 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 250-355 of human CCR8 (P51685). |
| Immunogen Sequence: | FWVPFNVVLFLTSLHSMHIL DGCSISQQLTYATHVTEIIS FTHCCVNPVIYAFVGEKFKK HLSEIFQKSCSQIFNYLGRQ MPRESCEKSSSCQQHSSRSS SVDYIL |
| Function | Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. |
| Protein Name | C-C Chemokine Receptor Type 8C-C Ckr-8Cc-Ckr-8Ccr-8Cc Chemokine Receptor Chemr1Cmkbrl2Chemokine Receptor-Like 1Ckr-L1Gpr-Cy6Gprcy6Ter1Cd Antigen Cdw198 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 8 antibodyAnti-C-C Ckr-8 antibodyAnti-Cc-Ckr-8 antibodyAnti-Ccr-8 antibodyAnti-Cc Chemokine Receptor Chemr1 antibodyAnti-Cmkbrl2 antibodyAnti-Chemokine Receptor-Like 1 antibodyAnti-Ckr-L1 antibodyAnti-Gpr-Cy6 antibodyAnti-Gprcy6 antibodyAnti-Ter1 antibodyAnti-Cd Antigen Cdw198 antibodyAnti-CCR8 antibodyAnti-CKRL1 antibodyAnti-CMKBR8 antibodyAnti-CMKBRL2 antibody |
Information sourced from Uniprot.org