| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C-C motif chemokine 8 (50-99 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCL8 |
| Gene ID: | 6355 |
| Uniprot ID: | CCL8_HUMAN |
| Immunogen Region: | 50-99 aa |
| Specificity: | MCP-2 Polyclonal Antibody detects endogenous levels of MCP-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the C-terminal region of human CCL8 at the amino acid range 50-99 |
| Post Translational Modifications | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. |
| Protein Name | C-C Motif Chemokine 8Hc14Monocyte Chemoattractant Protein 2Monocyte Chemotactic Protein 2Mcp-2Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 8 antibodyAnti-Hc14 antibodyAnti-Monocyte Chemoattractant Protein 2 antibodyAnti-Monocyte Chemotactic Protein 2 antibodyAnti-Mcp-2 antibodyAnti-Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 antibodyAnti-CCL8 antibodyAnti-MCP2 antibodyAnti-SCYA10 antibodyAnti-SCYA8 antibody |
Information sourced from Uniprot.org
