• Western blot analysis of lysates from wild type (WT) and 293T cells transfected with CCL25, using CCL25 rabbit polyclonal antibody (STJ116184) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-mouse IgG (H+L) (STJS000854) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 0. 5s.

Anti-CCL25 antibody (24-150) (STJ116184)

SKU:
STJ116184

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CCL25 (24-150) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL25
Gene ID: 6370
Uniprot ID: CCL25_HUMAN
Immunogen Region: 24-150
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-150 of human CCL25 (NP_005615.2).
Immunogen Sequence: QGVFEDCCLAYHYPIGWAVL RRAWTYRIQEVSGSCNLPAA IFYLPKRHRKVCGNPKSREV QRAMKLLDARNKVFAKLHHN TQTFQAGPHAVKKLSSGNSK LSSSKFSNPISSSKRNVSLL ISANSGL
Tissue Specificity Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Function Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 25
Chemokine Teck
Small-Inducible Cytokine A25
Thymus-Expressed Chemokine
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 25 antibody
Anti-Chemokine Teck antibody
Anti-Small-Inducible Cytokine A25 antibody
Anti-Thymus-Expressed Chemokine antibody
Anti-CCL25 antibody
Anti-SCYA25 antibody
Anti-TECK antibody

Information sourced from Uniprot.org

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