| Short Description : | Rabbit polyclonal CCL11 (1-97) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCL11 |
| Gene ID: | 6356 |
| Uniprot ID: | CCL11_HUMAN |
| Immunogen Region: | 1-97 |
| Immunogen Sequence: | MKVSAALLWLLLIAAAFSPQ GLAGPASVPTTCCFNLANRK IPLQRLESYRRITSGKCPQK AVIFKTKLAKDICADPKKKW VQDSMKYLDQKSPTPKP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human CCL11 (NP_002977.1). |
| Post Translational Modifications | O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. |
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Eotaxin antibodyAnti-C-C Motif Chemokine 11 antibodyAnti-Eosinophil Chemotactic Protein antibodyAnti-Small-Inducible Cytokine A11 antibodyAnti-CCL11 antibodyAnti-SCYA11 antibody |
Information sourced from Uniprot.org
