| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCKAR |
| Gene ID: | 886 |
| Uniprot ID: | CCKAR_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CCKAR (NP_000721.1). |
| Immunogen Sequence: | IPNLLKDFIFGSAVCKTTTY FMGTSVSVSTFNLVAISLER YGAICKPLQSRVWQTKSHAL KVIAATWCLSFTIMTPYPIY SNLVPFTKNNNQTANMCRFL L |
| Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Name | Cholecystokinin Receptor Type A Cck-A Receptor Cck-Ar Cholecystokinin-1 Receptor Cck1-R |
| Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-416476 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cholecystokinin Receptor Type A antibody Anti-Cck-A Receptor antibody Anti-Cck-Ar antibody Anti-Cholecystokinin-1 Receptor antibody Anti-Cck1-R antibody Anti-CCKAR antibody Anti-CCKRA antibody |
Information sourced from Uniprot.org