| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dynein regulatory complex subunit 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCDC65 |
| Gene ID: |
85478 |
| Uniprot ID: |
DRC2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of CCDC65 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human CCDC65 |
| Function | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. |
| Protein Name | Dynein Regulatory Complex Subunit 2Coiled-Coil Domain-Containing Protein 65Testis Development Protein Nyd-Sp28 |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum Basal BodyCell ProjectionCiliumFlagellumFlagellum Axoneme |
| Alternative Antibody Names | Anti-Dynein Regulatory Complex Subunit 2 antibodyAnti-Coiled-Coil Domain-Containing Protein 65 antibodyAnti-Testis Development Protein Nyd-Sp28 antibodyAnti-CCDC65 antibodyAnti-DRC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
