Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Dynein regulatory complex subunit 2 is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCDC65 |
Gene ID: | 85478 |
Uniprot ID: | DRC2_HUMAN |
Specificity: | This antibody detects endogenous levels of CCDC65 at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human CCDC65 |
Function | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. |
Protein Name | Dynein Regulatory Complex Subunit 2Coiled-Coil Domain-Containing Protein 65Testis Development Protein Nyd-Sp28 |
Cellular Localisation | CytoplasmCytoskeletonFlagellum Basal BodyCell ProjectionCiliumFlagellumFlagellum Axoneme |
Alternative Antibody Names | Anti-Dynein Regulatory Complex Subunit 2 antibodyAnti-Coiled-Coil Domain-Containing Protein 65 antibodyAnti-Testis Development Protein Nyd-Sp28 antibodyAnti-CCDC65 antibodyAnti-DRC2 antibody |
Information sourced from Uniprot.org