Anti-CBY1 antibody (2-50 aa) (STJ13100879)

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STJ13100879-100
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Short Description :Rabbit polyclonal anti-CBY1 (2-50 aa) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:CBY1
Gene ID:25776
Uniprot ID:CBY1_HUMAN
Immunogen:A synthetic peptide from aa region 2-50 of human CBY1 conjugated to an immunogenic carrier protein was used as the antigen.
Immunogen Region:2-50 aa
Specificity:Specific for CBY1.
Function Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Protein Name Protein Chibby Homolog 1
Arpp-Binding Protein
Cytosolic Leucine-Rich Protein
Pigea-14
Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1
Database Links Reactome: R-HSA-3769402
Cellular Localisation Nucleus Speckle
Cytoplasm
Cytoskeleton
Cilium Basal Body
Microtubule Organizing Center
Centrosome
Centriole
Golgi Apparatus
Trans-Golgi Network
Cell Projection
Cilium
Flagellum
Nucleus
Alternative Antibody Names Anti-Protein Chibby Homolog 1 antibody
Anti-Arpp-Binding Protein antibody
Anti-Cytosolic Leucine-Rich Protein antibody
Anti-Pigea-14 antibody
Anti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibody
Anti-CBY1 antibody
Anti-ARB1 antibody
Anti-C22orf2 antibody
Anti-CBY antibody
Anti-PGEA1 antibody
Anti-HRIHFB2025 antibody

Information sourced from Uniprot.org

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