Anti-CAST antibody (1-350) (STJ119179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAST (1-350) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAST |
| Gene ID | 831 |
| Uniprot ID | ICAL_HUMAN |
| Immunogen Region | 1-350 |
| Immunogen Sequence | MNPTETKAIPVSQQMEGPHL PNKKKHKKQAVKTEPEKKSQ STKLSVVHEKKSQEGKPKEH TEPKSLPKQASDTGSNDAHN KKAVSRSAEQQPSEKSTEPK TKPQDMISAGGESVAGITAI SGKPGDKKKEKKSLTPAVPV ESKPDKPSGKSGMDAALDDL IDTLGGPEETEEENTTYTGP EVSDPMSSTYIEELGKREVT IPPKYRELLAKPIGPDDAID ALSSDFTCGSPTAAGKKTE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CAST (NP_001177371.1). |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
| Protein Name | CalpastatinCalpain InhibitorSperm Bs-17 Component |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Calpastatin antibodyAnti-Calpain Inhibitor antibodyAnti-Sperm Bs-17 Component antibodyAnti-CAST antibody |
Information sourced from Uniprot.org