Anti-CapG antibody (1-348aa) [AT1D10] (STJA0041794)

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STJA0041794
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Host: Mouse
Applications: ELISA/WB/ICC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-CapG (1-348aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : AT1D10
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Purification: By protein-A affinity chromatography
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAPG
Gene ID: 822
Uniprot ID: CAPG_HUMAN
Immunogen Region: 1-348aa
Accession Number: AAH00728
Immunogen: Recombinant human CAPG (1-348aa) purified from E. coli
Tissue Specificity Macrophages and macrophage-like cells.
Post Translational Modifications The N-terminus is blocked.
Function Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Protein Name Macrophage-Capping Protein
Actin Regulatory Protein Cap-G
Database Links
Cellular Localisation Nucleus
Cytoplasm
Melanosome
Cell Projection
Lamellipodium
Ruffle
In Macrophages
May Be Predominantly Cytoplasmic
Nuclear Localization Was Observed In Fibroblasts
Present At The Membrane-Cytoplasm Interface
In Activated Macrophages
Concentrated In The Ruffles Of The Leading Lamellipodia
Alternative Antibody Names Anti-Macrophage-Capping Protein antibody
Anti-Actin Regulatory Protein Cap-G antibody
Anti-CAPG antibody
Anti-AFCP antibody
Anti-MCP antibody

Information sourced from Uniprot.org

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