| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S0MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLGN |
| Gene ID: | 1047 |
| Uniprot ID: | CLGN_HUMAN |
| Immunogen Region: | 180-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-350 of human Calmegin (O14967). |
| Immunogen Sequence: | FGPDKCGEDYKLHFIFRHKH PKTGVFEEKHAKPPDVDLKK FFTDRKTHLYTLVMNPDDTF EVLVDQTVVNKGSLLEDVVP PIKPPKEIEDPNDKKPEEWD ERAKIPDPSAVKPEDWDESE PAQIEDSSVVKPAGWLDDEP KFIPDPNAEKPDDWNEDTDG EWEAPQILNPA |
| Tissue Specificity | Detected in testis (at protein level). Detected in testis. |
| Function | Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions. |
| Protein Name | Calmegin |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Calmegin antibodyAnti-CLGN antibody |
Information sourced from Uniprot.org