Anti-CACNG2 antibody (C-Term) (STJA0003779)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Stargazin (C-Term) for use in WB in Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 ยตl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 ยตg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Cacng2 |
| Gene ID | 12300 |
| Uniprot ID | CCG2_MOUSE |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. |
| Immunogen Region | C-Term |
Additional Info
| Tissue Specificity | Brain. |
| Post Translational Modifications | Phosphorylation of Thr-321 by PKA impairs interaction with DLG1 and DLG4. |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-2 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-2 SubunitStargazinTransmembrane Ampar Regulatory Protein Gamma-2Tarp Gamma-2 |
| Database Links | Reactome: R-MMU-112308Reactome: -MMU-399719Reactome: -MMU-5682910 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibodyAnti-Stargazin antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-2 antibodyAnti-Tarp Gamma-2 antibodyAnti-Cacng2 antibodyAnti-Stg antibody |
Information sourced from Uniprot.org