Tissue Specificity | Detected in heart ventricle (at protein level). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. |
Function | Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit. |
Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-1Cab1Calcium Channel Voltage-Dependent Subunit Beta 1 |
Database Links | Reactome: R-HSA-112308Reactome: R-HSA-419037Reactome: R-HSA-5576892Reactome: R-HSA-5576893 |
Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic Side |
Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-1 antibodyAnti-Cab1 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 1 antibodyAnti-CACNB1 antibodyAnti-CACNLB1 antibody |
Information sourced from Uniprot.org