| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells. They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. Isoform 3: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells. They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. |
| Protein Name | Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1eBrain Calcium Channel IiBiiCalcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6Voltage-Gated Calcium Channel Subunit Alpha Cav2.3 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-422356 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1e antibodyAnti-Brain Calcium Channel Ii antibodyAnti-Bii antibodyAnti-Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.3 antibodyAnti-CACNA1E antibodyAnti-CACH6 antibodyAnti-CACNL1A6 antibody |
Information sourced from Uniprot.org
