Anti-CACNA1B antibody (990-1040 aa) (STJ13100950)

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STJ13100950-100
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Short Description :Rabbit polyclonal anti-CACNA1B (990-1040 aa) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/WB
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:IgG purified
Dilution Range:IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Formulation:Lyophilised
Storage Instruction:Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol:Cacna1b
Gene ID:12287
Uniprot ID:CAC1B_MOUSE
Immunogen:A synthetic peptide from aa region 990-1040 of mouse CACNA1B conjugated to blue carrier protein was used as the antigen.
Immunogen Region:990-1040 aa
Specificity:Specific for CACNA1B.
Post Translational Modifications Phosphorylated in vitro by CaM-kinase II, PKA, PKC and CGPK.
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals.
Protein Name Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1b
Brain Calcium Channel Iii
Biii
Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 5
Voltage-Gated Calcium Channel Subunit Alpha Cav2.2
Database Links Reactome: R-MMU-112308
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1b antibody
Anti-Brain Calcium Channel Iii antibody
Anti-Biii antibody
Anti-Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 5 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.2 antibody
Anti-Cacna1b antibody
Anti-Cach5 antibody
Anti-Cacnl1a5 antibody
Anti-Cchn1a antibody

Information sourced from Uniprot.org

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