• STJ70229 staining (1µg/ml) of human brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-CABP1 antibody (N-Term) (STJ70229)

SKU:
STJ70229-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CABP1 (N-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-Recommended for use at 0.5-2µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CABP1
Gene ID: 9478
Uniprot ID: CABP1_HUMAN
Immunogen Region: N-Term
Accession Number: NP_112482.1; NP_004267.2
Specificity: This antibody is expected to recognise both Human isoforms.
Immunogen Sequence: GNCVKYPLRNLS
Post Translational Modifications Phosphorylated. The phosphorylation regulates the activity.
Function Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina.
Protein Name Calcium-Binding Protein 1
Cabp1
Calbrain
Caldendrin
Database Links Reactome: R-HSA-9662360
Cellular Localisation Cytoplasm
Cytoskeleton
Perinuclear Region
Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Golgi Apparatus
Postsynaptic Density
L-Cabp1 Is Associated Most Likely With The Cytoskeletal Structures
Whereas S-Cabp1 Is Localized At Or Near The Plasma Membrane
Isoform L-Cabp1: Cytoplasm
Isoform S-Cabp1: Cytoplasm
Cell Cortex
S-Cabp1 Is Localized At Or Near The Plasma Membrane
Alternative Antibody Names Anti-Calcium-Binding Protein 1 antibody
Anti-Cabp1 antibody
Anti-Calbrain antibody
Anti-Caldendrin antibody
Anti-CABP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance