| Host: | Mouse |
| Applications: | FIA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CA19-9 for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 4701 |
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Formulation: | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | Store at 2–8 °C, and do not freeze. |
| Specificity: | Antibody recognizes carbohydrate antigen 19-9 (CA19-9). Does not recognize cancer antigens CA125 or CA15-3. Does not recognize sialylated Lewis x (sLex) or Lewis y carbohydrate structures. Minor cross-reactivity against sialylated Lewis c (sLec) carb |
| Immunogen: | Antibody binds to sialylated Lewis a (sLea) pentasaccharide. |
| Background | Carbohydrate antigen 19-9 (CA19-9) is a specific carbohydrate epitope called sialylated Lewis-a pentasaccharide, also known as sLea antigen. This epitope is found on several glycoproteins, including Mucin-1. In healthy individuals, the serum concentration of CA19-9 is low, but it increases during gastrointestinal malignancies, including pancreatic cancer, pancreatic or hepatobiliary adenocarcinoma, or colon cancer. |
Information sourced from Uniprot.org
